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New insights into the spatiotemporal localization of prothrombinase in vivo

The membrane-dependent interaction of factor Xa (FXa) with factor Va (FVa) forms prothrombinase and drives thrombin formation essential for hemostasis. Activated platelets are considered to provide the primary biological surface to support prothrombinase function. However, the question of how other...

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Autores principales: Ivanciu, Lacramioara, Krishnaswamy, Sriram, Camire, Rodney M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162104/
https://ncbi.nlm.nih.gov/pubmed/24869936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-565010
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