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Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
The prothrombinase complex, composed of the protease factor (f)Xa and cofactor fVa, efficiently converts prothrombin to thrombin by specific sequential cleavage at 2 sites. How the complex assembles and its mechanism of prothrombin processing are of central importance to human health and disease, be...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798993/ https://ncbi.nlm.nih.gov/pubmed/23869089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-06-511733 |
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