Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

The integrin family is composed of a series of 24 αβ heterodimer transmembrane adhesion receptors that mediate cell-cell and cell-extracellular matrix interactions. Adaptor molecules bearing immunoreceptor tyrosine-based activation motifs (ITAMs) have recently been shown to cooperate with specific i...

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Detalhes bibliográficos
Main Authors: Zhi, Huiying, Rauova, Lubica, Hayes, Vincent, Gao, Cunji, Boylan, Brian, Newman, Debra K., McKenzie, Steven E., Cooley, Brian C., Poncz, Mortimer, Newman, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591804/
https://ncbi.nlm.nih.gov/pubmed/23264598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-443325
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