Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase

IgG immune complexes contribute to the etiology and pathogenesis of numerous autoimmune disorders, including heparin-induced thrombocytopenia, systemic lupus erythematosus, rheumatoid- and collagen-induced arthritis, and chronic glomerulonephritis. Patients suffering from immune complex-related diso...

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Udgivet i:PLoS One
Main Authors: Zhi, Huiying, Dai, Jing, Liu, Junling, Zhu, Jieqing, Newman, Debra K., Gao, Cunji, Newman, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546160/
https://ncbi.nlm.nih.gov/pubmed/26291522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135738
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