Identification of FcγRIIa as the ITAM-bearing receptor mediating αIIbβ3 outside-in integrin signaling in human platelets

Immunoreceptor tyrosine-based activation motif (ITAM)–containing proteins have recently been demonstrated in macrophages and neutrophils to be required for cell surface integrins to transmit activation signals into the cell. To identify ITAM-bearing proteins that mediate signaling via the platelet-s...

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Hlavní autoři: Boylan, Brian, Gao, Cunji, Rathore, Vipul, Gill, Joan C., Newman, Debra K., Newman, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Hemostasis, Thrombosis, and Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556613/
https://ncbi.nlm.nih.gov/pubmed/18641368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-142125
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