Advances in the pathophysiology and treatment of heparin-induced thrombocytopenia

par McKenzie, Steven E., Sachais, Bruce S.
Publié dans Curr Opin Hematol (2014)

PKCδ Deficiency Enhances Megakaryopoiesis and Recovery from Thrombocytopenia

par Kostyak, John C., Bhavanasi, Dheeraj, Liverani, Elisabeta, McKenzie, Steven E., Kunapuli, Satya P.
Publié dans Arterioscler Thromb Vasc Biol (2014)

Cholesterol Enrichment of Human Monocyte/Macrophages Induces Surface Exposure of Phosphatidylserine and the Release of Biologically-Active Tissue Factor–Positive Microvesicles

par Liu, Ming-Lin, Reilly, Michael P., Casasanto, Peter, McKenzie, Steven E., Williams, Kevin Jon
Publié dans Arterioscler Thromb Vasc Biol (2006)

ASK1 Regulates Immune-Mediated Thrombocytopenia, Thrombosis, and Systemic Shock

par Patel, Pravin, Shaik, Noor F., Zhou, Yuhang, Golla, Kalyan, McKenzie, Steven E., Naik, Ulhas P.
Publié dans J Thromb Haemost (2020)

Bleeding and Thrombotic Adverse Events in Hospitalized Patients Under Empiric Treatment for Suspected Heparin-Induced Thrombocytopenia While Awaiting Confirmatory Testing

par Dykes, Kaitlyn C., Johnson, Cassandra A., Gong, Jerald Z., McKenzie, Steven E., Husseinzadeh, Holleh D.
Publié dans Clin Appl Thromb Hemost (2021)

CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

par Stolla, Moritz, Stefanini, Lucia, André, Pierrette, Ouellette, Timothy D., Reilly, Michael P., McKenzie, Steven E., Bergmeier, Wolfgang
Publié 2011

CalDAG-GEFI deficiency protects mice from FcγRIIa-mediated thrombotic thrombocytopenia induced by CD40L and β2-GPI immune complexes

par Amirkhosravi, Ali, Boulaftali, Yacine, Robles-Carrillo, Liza, Meyer, Todd, McKenzie, Steven E., Francis, John L., Bergmeier, Wolfgang
Publié dans J Thromb Haemost (2014)

Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

par Hayes, Vincent, Johnston, Ian, Arepally, Gowthami M., McKenzie, Steven E., Cines, Douglas B., Rauova, Lubica, Poncz, Mortimer
Publié dans J Clin Invest (2017)

Mice expressing low levels of CalDAG-GEFI exhibit markedly impaired platelet activation with minor impact on hemostasis

par Piatt, Raymond, Paul, David S., Lee, Robert H., McKenzie, Steven E., Parise, Leslie V., Cowley, Dale O., Cooley, Brian C., Bergmeier, Wolfgang
Publié dans Arterioscler Thromb Vasc Biol (2016)

TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)(346), a Regulatory Site of Syk

par Reppschläger, Kevin, Gosselin, Jeanne, Dangelmaier, Carol A., Thomas, Dafydd H., Carpino, Nick, McKenzie, Steven E., Kunapuli, Satya P., Tsygankov, Alexander Y.
Publié dans J Biol Chem (2016)

TULA-2 protein phosphatase suppresses activation of Syk through the GPVI platelet receptor for collagen by dephosphorylating Tyr(P)(346), a regulatory site of Syk.

par Reppschläger, Kevin, Gosselin, Jeanne, Dangelmaier, Carol A., Thomas, Dafydd H., Carpino, Nick, McKenzie, Steven E., Kunapuli, Satya P., Tsygankov, Alexander Y.
Publié dans J Biol Chem (2017)

Tyrosine Phosphorylation on Spleen Tyrosine Kinase (Syk) Is Differentially Regulated in Human and Murine Platelets by Protein Kinase C Isoforms

par Buitrago, Lorena, Bhavanasi, Dheeraj, Dangelmaier, Carol, Manne, Bhanu Kanth, Badolia, Rachit, Borgognone, Alessandra, Tsygankov, Alexander Y., McKenzie, Steven E., Kunapuli, Satya P.
Publié 2013

The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome

par Londin, Eric R, Hatzimichael, Eleftheria, Loher, Phillipe, Edelstein, Leonard, Shaw, Chad, Delgrosso, Kathleen, Fortina, Paolo, Bray, Paul F, McKenzie, Steven E, Rigoutsos, Isidore
Publié 2014

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

par Zhi, Huiying, Rauova, Lubica, Hayes, Vincent, Gao, Cunji, Boylan, Brian, Newman, Debra K., McKenzie, Steven E., Cooley, Brian C., Poncz, Mortimer, Newman, Peter J.
Publié 2013

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

par Tutwiler, Valerie, Madeeva, Daria, Ahn, Hyun Sook, Andrianova, Izabella, Hayes, Vincent, Zheng, X. Long, Cines, Douglas B., McKenzie, Steven E., Poncz, Mortimer, Rauova, Lubica
Publié dans Blood (2016)

TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists

par Kostyak, John C., Mauri, Benjamin R., Dangelmaier, Carol, Patel, Akruti, Zhou, Yuhang, Eble, Johannes A., Tsygankov, Alexander Y., McKenzie, Steven E., Kunapuli, Satya P.
Publié dans TH Open (2018)

Recommendations for the clinical and laboratory diagnosis of VITT against COVID‐19: Communication from the ISTH SSC Subcommittee on Platelet Immunology

par Nazy, Ishac, Sachs, Ulrich J., Arnold, Donald M., McKenzie, Steven E., Choi, Phil, Althaus, Karina, Ahlen, Maria Therese, Sharma, Ruchika, Grace, Rachael F., Bakchoul, Tamam
Publié dans J Thromb Haemost (2021)

MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression

par Teruel-Montoya, Raul, Kong, Xianguo, Abraham, Shaji, Ma, Lin, Kunapuli, Satya P., Holinstat, Michael, Shaw, Chad A., McKenzie, Steven E., Edelstein, Leonard C., Bray, Paul F.
Publié 2014

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

par Reilly, Michael P., Sinha, Uma, André, Pierrette, Taylor, Scott M., Pak, Yvonne, DeGuzman, Francis R., Nanda, Nisha, Pandey, Anjali, Stolla, Moritz, Bergmeier, Wolfgang, McKenzie, Steven E.
Publié 2011

Anti–miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice

par Zhou, Yuhang, Abraham, Shaji, Andre, Pierrette, Edelstein, Leonard C., Shaw, Chad A., Dangelmaier, Carol A., Tsygankov, Alexander Y., Kunapuli, Satya P., Bray, Paul F., McKenzie, Steven E.
Publié dans Blood (2015)