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PKCδ Deficiency Enhances Megakaryopoiesis and Recovery from Thrombocytopenia

OBJECTIVE: We previously determined that Protein Kinase C delta (PKCδ) regulates platelet function. However, the function of PKCδ in megakaryopoiesis is unknown. APPROACH, RESULTS: Using PKCδ(−/−) and WT littermate mice we found that deficiency of PKCδ caused an increase in white blood cell and plat...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Kostyak, John C., Bhavanasi, Dheeraj, Liverani, Elisabeta, McKenzie, Steven E., Kunapuli, Satya P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239172/
https://ncbi.nlm.nih.gov/pubmed/25359855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304492
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