CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

Platelet activation via Fcγ receptor IIA (FcγRIIA) is a critical event in immune-mediated thrombocytopenia and thrombosis syndromes (ITT). We recently identified signaling by the guanine nucleotide exchange factor CalDAG-GEFI and the adenosine diphosphate receptor P2Y12 as independent pathways leadi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Stolla, Moritz, Stefanini, Lucia, André, Pierrette, Ouellette, Timothy D., Reilly, Michael P., McKenzie, Steven E., Bergmeier, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148161/
https://ncbi.nlm.nih.gov/pubmed/21652673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-342352
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados