CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

Platelet activation via Fcγ receptor IIA (FcγRIIA) is a critical event in immune-mediated thrombocytopenia and thrombosis syndromes (ITT). We recently identified signaling by the guanine nucleotide exchange factor CalDAG-GEFI and the adenosine diphosphate receptor P2Y12 as independent pathways leadi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Stolla, Moritz, Stefanini, Lucia, André, Pierrette, Ouellette, Timothy D., Reilly, Michael P., McKenzie, Steven E., Bergmeier, Wolfgang
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Thrombosis and Hemostasis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148161/
https://ncbi.nlm.nih.gov/pubmed/21652673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-342352
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki