MicroRNAs in platelet production and activation

Por Edelstein, Leonard C., Bray, Paul F.
Publicado em 2011

The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-x(L)

Por Chen, Cailin, Edelstein, Leonard C., Gélinas, Céline
Publicado em 2000

Chromatin Modification and the Endothelial-specific Activation of the E-selectin Gene

Por Edelstein, Leonard C., Pan, Amy, Collins, Tucker
Publicado em 2005

NF-κB-Dependent Assembly of an Enhanceosome-Like Complex on the Promoter Region of Apoptosis Inhibitor Bfl-1/A1

Por Edelstein, Leonard C., Lagos, Lynn, Simmons, Matthew, Tirumalai, Hemamalini, Gélinas, Céline
Publicado em 2003

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis

Por Zong, Wei-Xing, Edelstein, Leonard C., Chen, Cailin, Bash, Judy, Gélinas, Céline
Publicado em 1999

Short Communication: Activation of Latent HIV Type 1 Gene Expression by Suberoylanilide Hydroxamic Acid (SAHA), an HDAC Inhibitor Approved for Use to Treat Cutaneous T Cell Lymphom...

Por Edelstein, Leonard C., Micheva-Viteva, Sophia, Phelan, Bradley D., Dougherty, Joseph P.
Publicado em 2009

Mechanism of race-dependent platelet activation through the PAR4 and Gq signaling axis

Por Tourdot, Benjamin E., Conaway, Stanley, Niisuke, Katrin, Edelstein, Leonard C, Bray, Paul F, Holinstat, Michael
Publicado no Arterioscler Thromb Vasc Biol (2014)

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP

Por Kong, Xianguo, Simon, Lukas M., Holinstat, Michael, Shaw, Chad A., Bray, Paul F., Edelstein, Leonard C.
Publicado no Thromb Haemost (2017)

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2

Por Simon, Lukas M., Chen, Edward S., Edelstein, Leonard C., Kong, Xianguo, Bhatlekar, Seema, Rigoutsos, Isidore, Bray, Paul F., Shaw, Chad A.
Publicado no Am J Hum Genet (2016)

Nuclear Factor κB-Dependent Activation of the Antiapoptotic bfl-1 Gene by the Epstein-Barr Virus Latent Membrane Protein 1 and Activated CD40 Receptor

Por D'Souza, Brendan N., Edelstein, Leonard C., Pegman, Pamela M., Smith, Sinéad M., Loughran, Sinéad T., Clarke, Ann, Mehl, Anja, Rowe, Martin, Gélinas, Céline, Walls, Dermot
Publicado em 2004

MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression

Por Teruel-Montoya, Raul, Kong, Xianguo, Abraham, Shaji, Ma, Lin, Kunapuli, Satya P., Holinstat, Michael, Shaw, Chad A., McKenzie, Steven E., Edelstein, Leonard C., Bray, Paul F.
Publicado em 2014

Anti–miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice

Por Zhou, Yuhang, Abraham, Shaji, Andre, Pierrette, Edelstein, Leonard C., Shaw, Chad A., Dangelmaier, Carol A., Tsygankov, Alexander Y., Kunapuli, Satya P., Bray, Paul F., McKenzie, Steven E.
Publicado no Blood (2015)

The complex transcriptional landscape of the anucleate human platelet

Por Bray, Paul F, McKenzie, Steven E, Edelstein, Leonard C, Nagalla, Srikanth, Delgrosso, Kathleen, Ertel, Adam, Kupper, Joan, Jing, Yi, Londin, Eric, Loher, Phillipe, Chen, Huang-Wen, Fortina, Paolo, Rigoutsos, Isidore
Publicado em 2013

Racial Difference in Human Platelet PAR4 Reactivity Reflects Expression of PCTP and miR-376c

Por Edelstein, Leonard C., Simon, Lukas M., Montoya, Raúl Teruel, Holinstat, Michael, Chen, Edward S., Bergeron, Angela, Kong, Xianguo, Nagalla, Srikanth, Mohandas, Narla, Cohen, David E., Dong, Jing-fei, Shaw, Chad, Bray, Paul F.
Publicado em 2013

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race

Por Edelstein, Leonard C., Simon, Lukas M., Lindsay, Cory R., Kong, Xianguo, Teruel-Montoya, Raúl, Tourdot, Benjamin E., Chen, Edward S., Ma, Lin, Coughlin, Shaun, Nieman, Marvin, Holinstat, Michael, Shaw, Chad A., Bray, Paul F.
Publicado no Blood (2014)

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics

Por Simon, Lukas M., Edelstein, Leonard C., Nagalla, Srikanth, Woodley, Angela B., Chen, Edward S., Kong, Xianguo, Ma, Lin, Fortina, Paolo, Kunapuli, Satya, Holinstat, Michael, McKenzie, Steven E., Dong, Jing-fei, Shaw, Chad A., Bray, Paul F.
Publicado em 2014

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity

Por Nagalla, Srikanth, Shaw, Chad, Kong, Xianguo, Kondkar, Altaf A., Edelstein, Leonard C., Ma, Lin, Chen, Junmei, McKnight, G. Stanley, López, José A., Yang, Linghai, Jin, Ying, Bray, Molly S., Leal, Suzanne M., Dong, Jing-fei, Bray, Paul F.
Publicado em 2011

High-throughput Screening Uncovers a Compound That Activates Latent HIV-1 and Acts Cooperatively with a Histone Deacetylase (HDAC) Inhibitor

Por Micheva-Viteva, Sofiya, Kobayashi, Yoshifumi, Edelstein, Leonard C., Pacchia, Annmarie L., Lee, Hui-Ling Rose, Graci, Jason D., Breslin, Jamie, Phelan, Bradley D., Miller, Leia K., Colacino, Joseph M., Gu, Zhengxian, Ron, Yacov, Peltz, Stuart W., Dougherty, Joseph P.
Publicado em 2011

Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

Por Michael, James V., Wurtzel, Jeremy G. T., Mao, Guang Fen, Rao, A. Koneti, Kolpakov, Mikhail A., Sabri, Abdelkarim, Hoffman, Nicholas E., Rajan, Sudarsan, Tomar, Dhanendra, Madesh, Muniswamy, Nieman, Marvin T., Yu, Johnny, Edelstein, Leonard C., Rowley, Jesse W., Weyrich, Andrew S., Goldfinger, Lawrence E.
Publicado no Blood (2017)

Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation under Shear Stress

Por Edelstein, Leonard C., Luna, Elizabeth J., Gibson, Ian B., Bray, Molly, Jin, Ying, Kondkar, Altaf, Nagalla, Srikanth, Hadjout-Rabi, Nacima, Smith, Tara C., Covarrubias, Daniel, Jones, Stephen N., Ahmad, Firdos, Stolla, Moritz, Kong, Xianguo, Fang, Zhiyou, Bergmeier, Wolfgang, Shaw, Chad, Leal, Suzanne M., Bray, Paul F.
Publicado em 2012