QR-kod

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis

Bcl-2-family proteins are key regulators of the apoptotic response. Here, we demonstrate that the pro-survival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB. We show that bfl-1 gene expression is dependent on NF-κB activity and that it can substitute for NF-κB to suppress TNFα-i...

Full beskrivning

Sparad:
I publikationen:Genes Dev
Huvudupphov: Zong, Wei-Xing, Edelstein, Leonard C., Chen, Cailin, Bash, Judy, Gélinas, Céline
Materialtyp: Artigo
Språk:Inglês
Utgiven: Cold Spring Harbor Laboratory Press 1999
Ämnen:
Research Communication
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316475/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.382
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk