The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis
Bcl-2-family proteins are key regulators of the apoptotic response. Here, we demonstrate that the pro-survival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB. We show that bfl-1 gene expression is dependent on NF-κB activity and that it can substitute for NF-κB to suppress TNFα-i...
Kaydedildi:
| Yayımlandı: | Genes Dev |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
1999
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.382 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|
