Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity

Consistent with the constitutive activation of Rel/NF-κB in human hematopoietic tumors, the v-Rel oncoprotein induces aggressive leukemia/lymphomas in animal models. v-Rel is thus a valuable tool to characterize the role of Rel/NF-κB in cancer and the mechanisms involved. Prior studies by our group...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Rayet, Béatrice, Fan, Yongjun, Gélinas, Céline
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1520-1533.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!