Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity

Consistent with the constitutive activation of Rel/NF-κB in human hematopoietic tumors, the v-Rel oncoprotein induces aggressive leukemia/lymphomas in animal models. v-Rel is thus a valuable tool to characterize the role of Rel/NF-κB in cancer and the mechanisms involved. Prior studies by our group...

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Bibliographic Details
Main Authors: Rayet, Béatrice, Fan, Yongjun, Gélinas, Céline
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151695/
https://ncbi.nlm.nih.gov/pubmed/12588973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1520-1533.2003
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