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Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity
Consistent with the constitutive activation of Rel/NF-κB in human hematopoietic tumors, the v-Rel oncoprotein induces aggressive leukemia/lymphomas in animal models. v-Rel is thus a valuable tool to characterize the role of Rel/NF-κB in cancer and the mechanisms involved. Prior studies by our group...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151695/ https://ncbi.nlm.nih.gov/pubmed/12588973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1520-1533.2003 |
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