Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity

Consistent with the constitutive activation of Rel/NF-κB in human hematopoietic tumors, the v-Rel oncoprotein induces aggressive leukemia/lymphomas in animal models. v-Rel is thus a valuable tool to characterize the role of Rel/NF-κB in cancer and the mechanisms involved. Prior studies by our group...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Rayet, Béatrice, Fan, Yongjun, Gélinas, Céline
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1520-1533.2003
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