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Short Communication: Activation of Latent HIV Type 1 Gene Expression by Suberoylanilide Hydroxamic Acid (SAHA), an HDAC Inhibitor Approved for Use to Treat Cutaneous T Cell Lymphoma

The ability of HIV to establish a latent infection causes life-long virus persistence, even after long-term highly active antiretroviral therapy (HAART). The role that latency is playing in preventing clearance of the virus infection has become evident in recent years. Patients who have been success...

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Autori principali: Edelstein, Leonard C., Micheva-Viteva, Sophia, Phelan, Bradley D., Dougherty, Joseph P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828260/
https://ncbi.nlm.nih.gov/pubmed/19689202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0294
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