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Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells

Mantle cell lymphoma (MCL) has a chromosomal translocation resulting in the expression of the cyclin D1 gene driven by the powerful enhancer of the immunoglobulin heavy chain gene, leading to uncontrolled, overexpressed cyclin D1 protein. We showed that suberoylanilide hydroxamic acid (SAHA; vorinos...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kawamata, Norihiko, Chen, John, Koeffler, H. Phillip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988938/
https://ncbi.nlm.nih.gov/pubmed/17606765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-026344
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