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Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid

Histone deacetylases (HDACs) act on histones within the nucleosome-bound promoter of human immunodeficiency virus type 1 (HIV-1) to maintain proviral latency. HDAC inhibition leads to promoter expression and the escape of HIV from latency. We evaluated the ability of the potent inhibitor recently li...

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Detalhes bibliográficos
Main Authors: Archin, Nancie M., Espeseth, Amy, Parker, Daniel, Cheema, Manzoor, Hazuda, Daria, Margolis, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853863/
https://ncbi.nlm.nih.gov/pubmed/19239360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0191
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