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Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors
OBJECTIVES: A family of histone deacetylases (HDACs) mediates chromatin remodeling, and repression of gene expression. Deacetylation of histones within the HIV-1 long terminal repeat (LTR) by HDACs plays a key role in the maintenance of latency, whereas acetylation of histones about the LTR is linke...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809117/ https://ncbi.nlm.nih.gov/pubmed/19590405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32832ec1dc |
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