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Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

OBJECTIVES: A family of histone deacetylases (HDACs) mediates chromatin remodeling, and repression of gene expression. Deacetylation of histones within the HIV-1 long terminal repeat (LTR) by HDACs plays a key role in the maintenance of latency, whereas acetylation of histones about the LTR is linke...

詳細記述

保存先:
書誌詳細
主要な著者: Archin, Nancie M., Keedy, Kara S., Espeseth, Amy, Dang, Herbert, Hazuda, Daria J., Margolis, David M.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809117/
https://ncbi.nlm.nih.gov/pubmed/19590405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32832ec1dc
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