A Limited Group of Class I Histone Deacetylases Acts To Repress Human Immunodeficiency Virus Type 1 Expression

Silencing of the integrated human immunodeficiency virus type 1 (HIV-1) genome in resting CD4(+) T cells is a significant contributor to the persistence of infection, allowing the virus to evade both immune detection and pharmaceutical attack. Nonselective histone deacetylase (HDAC) inhibitors are c...

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Hlavní autoři: Keedy, Kara S., Archin, Nancie M., Gates, Adam T., Espeseth, Amy, Hazuda, Daria J., Margolis, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682072/
https://ncbi.nlm.nih.gov/pubmed/19279091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02585-08
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