c-Myc and Sp1 Contribute to Proviral Latency by Recruiting Histone Deacetylase 1 to the Human Immunodeficiency Virus Type 1 Promoter

Histone deacetylase (HDAC) inhibitors such as valproic acid (VPA) induce the expression of quiescent proviral human immunodeficiency virus type 1 (HIV-1) and may deplete proviral infection in vivo. To uncover novel molecular mechanisms that maintain HIV latency, we sought cellular mRNAs whose expres...

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Bibliographic Details
Main Authors: Jiang, Guochun, Espeseth, Amy, Hazuda, Daria J., Margolis, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045540/
https://ncbi.nlm.nih.gov/pubmed/17670825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01208-07
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