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Quiescence Promotes Latent HIV Infection and Resistance to Reactivation from Latency with Histone Deacetylase Inhibitors

Human immunodeficiency virus type 1 (HIV-1) establishes transcriptionally silent latent infections in resting memory T cells and hematopoietic stem and progenitor cells (HSPCs), which allows the virus to persist in infected individuals despite antiretroviral therapy. Developing in vitro models of HI...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Painter, Mark M., Zaikos, Thomas D., Collins, Kathleen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709582/
https://ncbi.nlm.nih.gov/pubmed/29021396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01080-17
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