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Reactivation of latent HIV by histone deacetylase inhibitors

Latent HIV persists in CD4+ T cells in infected patients under antiretroviral therapy (ART). Latency is associated with transcriptional silencing of the integrated provirus and driven, at least in part, by histone deacetylases (HDACs), a family of chromatin associated proteins that regulate histone...

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Bibliografiset tiedot
Päätekijät: Shirakawa, Kotaro, Chavez, Leonard, Hakre, Shweta, Calvanese, Vincenzo, Verdin, Eric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685471/
https://ncbi.nlm.nih.gov/pubmed/23517573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2013.02.005
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