Reactivation of latent HIV by histone deacetylase inhibitors

Latent HIV persists in CD4+ T cells in infected patients under antiretroviral therapy (ART). Latency is associated with transcriptional silencing of the integrated provirus and driven, at least in part, by histone deacetylases (HDACs), a family of chromatin associated proteins that regulate histone...

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Bibliographic Details
Main Authors:	Shirakawa, Kotaro, Chavez, Leonard, Hakre, Shweta, Calvanese, Vincenzo, Verdin, Eric
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3685471/ https://ncbi.nlm.nih.gov/pubmed/23517573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2013.02.005
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Reactivation of latent HIV by histone deacetylase inhibitors

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