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Reactivation of latent HIV by histone deacetylase inhibitors
Latent HIV persists in CD4+ T cells in infected patients under antiretroviral therapy (ART). Latency is associated with transcriptional silencing of the integrated provirus and driven, at least in part, by histone deacetylases (HDACs), a family of chromatin associated proteins that regulate histone...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685471/ https://ncbi.nlm.nih.gov/pubmed/23517573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2013.02.005 |
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