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HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells

Highly active antiretroviral therapy (HAART) suppresses human immunodeficiency virus (HIV) replication to undetectable levels but cannot fully eradicate the virus because a small reservoir of CD4(+) T cells remains latently infected. Since HIV efficiently infects only activated CD4(+) T cells and si...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Chavez, Leonard, Calvanese, Vincenzo, Verdin, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466167/
https://ncbi.nlm.nih.gov/pubmed/26067822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004955
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