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Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP

Platelet activation in response to stimulation of the Protease Activated Receptor 4 (PAR4) receptor differs by race. One factor that contributes to this difference is the expression level of Phosphatidylcholine Transfer Protein (PCTP), a regulator of platelet PAR4 function. We have conducted an expr...

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Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Kong, Xianguo, Simon, Lukas M., Holinstat, Michael, Shaw, Chad A., Bray, Paul F., Edelstein, Leonard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512274/
https://ncbi.nlm.nih.gov/pubmed/28251237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH16-09-0692
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