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Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is characterized by a high incidence of thrombosis, unlike other antibody-mediated causes of thrombocytopenia. We have shown that monocytes complexed with surface-bound platelet factor 4 (PF4) activated by HIT antibodies contribute to the prothrombotic state in...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731847/ https://ncbi.nlm.nih.gov/pubmed/26518435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-539262 |
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