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Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder initiated by antibodies to platelet factor 4 (PF4)/heparin complexes. PF4 released from platelets binds to surface glycosaminoglycans on hematopoietic and vascular cells that are heterogenous in composition and differ in affinity for...
Tallennettuna:
| Julkaisussa: | Blood |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097133/ https://ncbi.nlm.nih.gov/pubmed/29914979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-830737 |
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