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Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder initiated by antibodies to platelet factor 4 (PF4)/heparin complexes. PF4 released from platelets binds to surface glycosaminoglycans on hematopoietic and vascular cells that are heterogenous in composition and differ in affinity for...
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| Udgivet i: | Blood |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097133/ https://ncbi.nlm.nih.gov/pubmed/29914979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-830737 |
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