Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a life- and limb-threatening thrombotic disorder that develops after exposure to heparin, often in the setting of inflammation. We have shown previously that HIT is associated with antibodies to complexes that form between platelet factor 4 and glycosaminogl...

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Hlavní autoři: Rauova, Lubica, Hirsch, Jessica D., Greene, Teshell K., Zhai, Li, Hayes, Vincent M., Kowalska, M. Anna, Cines, Douglas B., Poncz, Mortimer
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012595/
https://ncbi.nlm.nih.gov/pubmed/20724543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-276964
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