Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a life- and limb-threatening thrombotic disorder that develops after exposure to heparin, often in the setting of inflammation. We have shown previously that HIT is associated with antibodies to complexes that form between platelet factor 4 and glycosaminogl...

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Autors principals: Rauova, Lubica, Hirsch, Jessica D., Greene, Teshell K., Zhai, Li, Hayes, Vincent M., Kowalska, M. Anna, Cines, Douglas B., Poncz, Mortimer
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012595/
https://ncbi.nlm.nih.gov/pubmed/20724543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-276964
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