Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation

Protein arginylation by arginyl–transfer RNA protein transferase (ATE1) is emerging as a regulator protein function that is reminiscent of phosphorylation. For example, arginylation of β-actin has been found to regulate lamellipodial formation at the leading edge in fibroblasts. This finding suggest...

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Главные авторы: Lian, Lurong, Suzuki, Aae, Hayes, Vincent, Saha, Sougata, Han, Xuemei, Xu, Tao, Yates, John R, Poncz, Mortimer, Kashina, Anna, Abrams, Charles S.
Формат: Artigo
Язык:Inglês
Опубликовано: Ferrata Storti Foundation 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943321/
https://ncbi.nlm.nih.gov/pubmed/24293517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.093047
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