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Differential Arginylation of Actin Isoforms is Regulated by Coding-Sequence-Dependent Degradation
The mammalian cytoskeletal proteins β- and γ-actin are highly homologous, but only β-actin is N-terminally arginylated, which regulates its function. Here we examined the metabolic fate of exogenously expressed arginylated and non-arginylated actin isoforms. Arginylated γ-actin, unlike β-, was highl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941909/ https://ncbi.nlm.nih.gov/pubmed/20847274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191701 |
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