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Arginylation Regulates Intracellular Actin Polymer Level by Modulating Actin Properties and Binding of Capping and Severing Proteins

Actin arginylation regulates lamella formation in motile fibroblasts, but the underlying molecular mechanisms are unknown. To understand how arginylation affects the actin cytoskeleton, we investigated the biochemical properties and the structural organization of actin filaments in wild-type and arg...

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Detalhes bibliográficos
Main Authors: Saha, Sougata, Mundia, Maureen M., Zhang, Fangliang, Demers, Ryan W., Korobova, Farida, Svitkina, Tatyana, Perieteanu, Alex A., Dawson, John F., Kashina, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854093/
https://ncbi.nlm.nih.gov/pubmed/20181827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0829
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