Understanding platelet generation from megakaryocytes: implications for in vitro–derived platelets

Por Sim, Xiuli, Poncz, Mortimer, Gadue, Paul, French, Deborah L.
Publicado no Blood (2016)

High-Throughput Screening Assay for Embryoid Body Differentiation of Human Embryonic Stem Cells

Por Outten, Joel T., Gadue, Paul, French, Deborah L., Diamond, Scott L.
Publicado em 2012

OCT4 Coordinates with WNT Signaling to Pre-pattern Chromatin at the SOX17 Locus during Human ES Cell Differentiation into Definitive Endoderm

Por Ying, Lei, Mills, Jason A., French, Deborah L., Gadue, Paul
Publicado no Stem Cell Reports (2015)

αIIbβ3 biogenesis is controlled by engagement of αIIb in the calnexin cycle via the N15-linked glycan

Por Mitchell, W. Beau, Li, JiHong, French, Deborah L., Coller, Barry S.
Publicado em 2006

A Doxycycline-Inducible System for Genetic Correction of iPSC Disease Models

Por Sim, Xiuli, Cardenas-Diaz, Fabian L., French, Deborah L., Gadue, Paul
Publicado no Methods Mol Biol (2016)

Challenges and promises for the development of donor-independent platelet transfusions

Por Lambert, Michele P., Sullivan, Spencer K., Fuentes, Rudy, French, Deborah L., Poncz, Mortimer
Publicado em 2013

MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells

Por Kamat, Viraj, Paluru, Prasuna, Myint, Melissa, French, Deborah L., Gadue, Paul, Diamond, Scott L.
Publicado em 2014

Utilization of the AAVS1 Safe Harbor Locus for Hematopoietic Specific Transgene Expression and Gene Knockdown in Human ES Cells

Por Tiyaboonchai, Amita, Mac, Helen, Shamsedeen, Razveen, Mills, Jason A., Kishore, Siddarth, French, Deborah L., Gadue, Paul
Publicado em 2014

Integrin β3 regions controlling binding of murine mAb 7E3: Implications for the mechanism of integrin αIIbβ3 activation

Por Artoni, Andrea, Li, JiHong, Mitchell, Beau, Ruan, Jian, Takagi, Junichi, Springer, Timothy A., French, Deborah L., Coller, Barry S.
Publicado em 2004

CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes

Por Zhang, Nanyan, Zhi, Huiying, Curtis, Brian R., Rao, Sridhar, Jobaliya, Chintan, Poncz, Mortimer, French, Deborah L., Newman, Peter J.
Publicado no Blood (2016)

Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia

Por Ge, Jingping, Apicella, Marisa, Mills, Jason A., Garçon, Loïc, French, Deborah L., Weiss, Mitchell J., Bessler, Monica, Mason, Philip J.
Publicado no PLoS One (2015)

Development and Function of Myeloid-Derived Suppressor Cells Generated From Mouse Embryonic and Hematopoietic Stem Cells

Por Zhou, Zuping, French, Deborah L., Ma, Ge, Eisenstein, Samuel, Chen, Ying, Divino, Celia M., Keller, Gordon, Chen, Shu-Hsia, Pan, Ping-Ying
Publicado no Stem Cells (2010)

The Negative Impact of Wnt Signaling on Megakaryocyte and Primitive Erythroid Progenitors Derived From Human Embryonic Stem Cells

Por Paluru, Prasuna, Hudock, Kristin M., Cheng, Xin, Mills, Jason A., Ying, Lei, Galvão, Aline M., Lu, Lin, Tiyaboonchai, Amita, Sim, Xiuli, Sullivan, Spencer K., French, Deborah L., Gadue, Paul
Publicado em 2013

Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Por Wang, Yuhuan, Hayes, Vincent, Jarocha, Danuta, Sim, Xiuli, Harper, Dawn C., Fuentes, Rudy, Sullivan, Spencer K., Gadue, Paul, Chou, Stella T., Torok-Storb, Beverly J., Marks, Michael S., French, Deborah L., Poncz, Mortimer
Publicado no Blood (2015)

Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector

Por Sommer, Andreia Gianotti, Rozelle, Sarah S., Sullivan, Spencer, Mills, Jason A., Park, Seon-Mi, Smith, Brenden W., Iyer, Amulya M., French, Deborah L., Kotton, Darrell N., Gadue, Paul, Murphy, George J., Mostoslavsky, Gustavo
Publicado em 2012

Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients

Por Garçon, Loïc, Ge, Jingping, Manjunath, Shwetha H., Mills, Jason A., Apicella, Marisa, Parikh, Shefali, Sullivan, Lisa M., Podsakoff, Gregory M., Gadue, Paul, French, Deborah L., Mason, Philip J., Bessler, Monica, Weiss, Mitchell J.
Publicado em 2013

HUMAN DEFINITIVE HAEMOGENIC ENDOTHELIUM AND ARTERIAL VASCULAR ENDOTHELIUM REPRESENT DISTINCT LINEAGES

Por Ditadi, Andrea, Sturgeon, Christopher M., Tober, Joanna, Awong, Geneve, Kennedy, Marion, Phillips, Amanda, Azzola, Lisa, Ng, Elizabeth S., Stanley, Edouard, French, Deborah L., Cheng, Xin, Gadue, Paul, Speck, Nancy, Elefanty, Andrew G., Keller, Gordon
Publicado no Nat Cell Biol (2015)

Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem Cells

Por Cheng, Xin, Ying, Lei, Lu, Lin, Galvão, Aline M., Mills, Jason A., Lin, Henry C., Kotton, Darrell N., Shen, Steven S., Nostro, M. Cristina, Choi, John Kim, Weiss, Mitchell J., French, Deborah L., Gadue, Paul
Publicado em 2012

GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells

Por Tiyaboonchai, Amita, Cardenas-Diaz, Fabian L., Ying, Lei, Maguire, Jean Ann, Sim, Xiuli, Jobaliya, Chintan, Gagne, Alyssa L., Kishore, Siddharth, Stanescu, Diana E., Hughes, Nkecha, De Leon, Diva D., French, Deborah L., Gadue, Paul
Publicado no Stem Cell Reports (2017)

Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia

Por Gandre-Babbe, Shilpa, Paluru, Prasuna, Aribeana, Chiaka, Chou, Stella T., Bresolin, Silvia, Lu, Lin, Sullivan, Spencer K., Tasian, Sarah K., Weng, Julie, Favre, Helene, Choi, John K., French, Deborah L., Loh, Mignon L., Weiss, Mitchell J.
Publicado em 2013