Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Thrombopoiesis is the process by which megakaryocytes release platelets that circulate as uniform small, disc-shaped anucleate cytoplasmic fragments with critical roles in hemostasis and related biology. The exact mechanism of thrombopoiesis and the maturation pathways of platelets released into the...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Yuhuan, Hayes, Vincent, Jarocha, Danuta, Sim, Xiuli, Harper, Dawn C., Fuentes, Rudy, Sullivan, Spencer K., Gadue, Paul, Chou, Stella T., Torok-Storb, Beverly J., Marks, Michael S., French, Deborah L., Poncz, Mortimer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458801/
https://ncbi.nlm.nih.gov/pubmed/25852052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-593053
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