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Understanding platelet generation from megakaryocytes: implications for in vitro–derived platelets

Platelets are anucleate cytoplasmic discs derived from megakaryocytes that circulate in the blood and have major roles in hemostasis, thrombosis, inflammation, and vascular biology. Platelet transfusions are required to prevent the potentially life-threatening complications of severe thrombocytopeni...

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Библиографические подробности
Опубликовано в: :Blood
Главные авторы: Sim, Xiuli, Poncz, Mortimer, Gadue, Paul, French, Deborah L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786833/
https://ncbi.nlm.nih.gov/pubmed/26787738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-607929
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