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Understanding platelet generation from megakaryocytes: implications for in vitro–derived platelets

Platelets are anucleate cytoplasmic discs derived from megakaryocytes that circulate in the blood and have major roles in hemostasis, thrombosis, inflammation, and vascular biology. Platelet transfusions are required to prevent the potentially life-threatening complications of severe thrombocytopeni...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Sim, Xiuli, Poncz, Mortimer, Gadue, Paul, French, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786833/
https://ncbi.nlm.nih.gov/pubmed/26787738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-607929
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