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Induced Pluripotent Stem Cell-Derived Megakaryocytes and Platelets for Disease Modeling and Clinical Use

Platelets, derived from megakaryocytes, are anucleate cytoplasmic discs that circulate in the blood stream and play major roles in hemostasis, inflammation, and vascular biology. Platelet transfusions are utilized in a variety of medical settings to prevent life-threatening thrombocytopenia due to c...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Borst, Sara, Sim, Xiuli, Poncz, Mortimer, French, Deborah L., Gadue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675007/
https://ncbi.nlm.nih.gov/pubmed/28982668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309197
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