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Induced Pluripotent Stem Cell-Derived Megakaryocytes and Platelets for Disease Modeling and Clinical Use

Platelets, derived from megakaryocytes, are anucleate cytoplasmic discs that circulate in the blood stream and play major roles in hemostasis, inflammation, and vascular biology. Platelet transfusions are utilized in a variety of medical settings to prevent life-threatening thrombocytopenia due to c...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Borst, Sara, Sim, Xiuli, Poncz, Mortimer, French, Deborah L., Gadue, Paul
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675007/
https://ncbi.nlm.nih.gov/pubmed/28982668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309197
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