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Understanding platelet generation from megakaryocytes: implications for in vitro–derived platelets

Platelets are anucleate cytoplasmic discs derived from megakaryocytes that circulate in the blood and have major roles in hemostasis, thrombosis, inflammation, and vascular biology. Platelet transfusions are required to prevent the potentially life-threatening complications of severe thrombocytopeni...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Sim, Xiuli, Poncz, Mortimer, Gadue, Paul, French, Deborah L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786833/
https://ncbi.nlm.nih.gov/pubmed/26787738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-607929
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