Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector

Through the ectopic expression of four transcription factors, Oct4, Klf4, Sox2 and cMyc, human somatic cells can be converted to a pluripotent state, generating so-called induced pluripotent stem cells (iPSCs)(1-4). Patient-specific iPSCs lack the ethical concerns that surround embryonic stem cells...

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Detalhes bibliográficos
Main Authors: Sommer, Andreia Gianotti, Rozelle, Sarah S., Sullivan, Spencer, Mills, Jason A., Park, Seon-Mi, Smith, Brenden W., Iyer, Amulya M., French, Deborah L., Kotton, Darrell N., Gadue, Paul, Murphy, George J., Mostoslavsky, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Stem Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499070/
https://ncbi.nlm.nih.gov/pubmed/23149977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4327
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