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iPS Cell Generation Using a Single Lentiviral Stem Cell Cassette
Induced Pluripotent Stem (iPS) cells can be generated using retroviral vectors expressing Oct4, Klf4, Sox2 and cMyc. Most prior studies have required multiple retroviral vectors for reprogramming, resulting in high numbers of genomic integrations in iPS cells and limiting their use for therapeutic a...
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| Udgivet i: | Stem Cells |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848035/ https://ncbi.nlm.nih.gov/pubmed/19096035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-1075 |
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