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Dual-promoter lentiviral system allows inducible expression of noxious proteins in macrophages

In-depth studies of innate immunity require efficient genetic manipulation of macrophages, which is especially difficult in primary macrophages. We have developed a lentiviral system for inducible gene expression both in macrophage cell lines and in primary macrophages. A transgenic mouse strain C3H...

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Bibliografiske detaljer
Main Authors: Pan, Hui, Mostoslavsky, Gustavo, Eruslanov, Evgeny, Kotton, Darrell N., Kramnik, Igor
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244810/
https://ncbi.nlm.nih.gov/pubmed/17967462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.09.009
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