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Dual-promoter lentiviral system allows inducible expression of noxious proteins in macrophages
In-depth studies of innate immunity require efficient genetic manipulation of macrophages, which is especially difficult in primary macrophages. We have developed a lentiviral system for inducible gene expression both in macrophage cell lines and in primary macrophages. A transgenic mouse strain C3H...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2244810/ https://ncbi.nlm.nih.gov/pubmed/17967462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.09.009 |
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