Lentiviral Delivery of RNAi for In Vivo Lineage-Specific Modulation of Gene Expression in Mouse Lung Macrophages

Although RNA interference (RNAi) has become a ubiquitous laboratory tool since its discovery 12 years ago, in vivo delivery to selected cell types remains a major technical challenge. Here, we report the use of lentiviral vectors for long-term in vivo delivery of RNAi selectively to resident alveola...

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Bibliografiske detaljer
Main Authors: Wilson, Andrew A, Kwok, Letty W, Porter, Emily L, Payne, Julie G, McElroy, Gregory S, Ohle, Sarah J, Greenhill, Sara R, Blahna, Matthew T, Yamamoto, Kazuko, Jean, Jyh C, Mizgerd, Joseph P, Kotton, Darrell N
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616534/
https://ncbi.nlm.nih.gov/pubmed/23403494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.19
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