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Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
Directed gene transfer into specific cell lineages in vivo is an attractive approach for both modulating gene expression and correcting inherited mutations such as emphysema caused by human α1 antitrypsin (hAAT) deficiency. However, somatic tissues are mainly comprised of heterogeneous, differentiat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798672/ https://ncbi.nlm.nih.gov/pubmed/20038801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36666 |
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