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Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
Directed gene transfer into specific cell lineages in vivo is an attractive approach for both modulating gene expression and correcting inherited mutations such as emphysema caused by human α1 antitrypsin (hAAT) deficiency. However, somatic tissues are mainly comprised of heterogeneous, differentiat...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798672/ https://ncbi.nlm.nih.gov/pubmed/20038801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36666 |
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