Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity

During pneumococcal pneumonia, antibacterial defense requires the orchestrated expression of innate immunity mediators, initiated by alveolar macrophages and dependent on transcription driven by nuclear factor κB (NF-κB). Such immune pressure may select for pneumococci, which avoid or subvert macrop...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Coleman, Fadie T, Blahna, Matthew T, Kamata, Hirofumi, Yamamoto, Kazuko, Zabinski, Mary C, Kramnik, Igor, Wilson, Andrew A, Kotton, Darrell N, Quinton, Lee J, Jones, Matthew R, Pelton, Stephen I, Mizgerd, Joseph P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279164/
https://ncbi.nlm.nih.gov/pubmed/28368460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix159
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