Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines

Induced pluripotent stem cells (iPSCs) hold great promise for modeling human hematopoietic diseases. However, intrinsic variability in the capacities of different iPSC lines for hematopoietic development complicates comparative studies and is currently unexplained. We created and analyzed 3 separate...

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Detalhes bibliográficos
Main Authors: Mills, Jason A., Wang, Kai, Paluru, Prasuna, Ying, Lei, Lu, Lin, Galvão, Aline M., Xu, Dongbin, Yao, Yu, Sullivan, Spencer K., Sullivan, Lisa M., Mac, Helen, Omari, Amel, Jean, Jyh-Chang, Shen, Steve, Gower, Adam, Spira, Avi, Mostoslavsky, Gustavo, Kotton, Darrell N., French, Deborah L., Weiss, Mitchell J., Gadue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778548/
https://ncbi.nlm.nih.gov/pubmed/23940280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-484444
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