Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector

Through the ectopic expression of four transcription factors, Oct4, Klf4, Sox2 and cMyc, human somatic cells can be converted to a pluripotent state, generating so-called induced pluripotent stem cells (iPSCs)(1-4). Patient-specific iPSCs lack the ethical concerns that surround embryonic stem cells...

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Détails bibliographiques
Auteurs principaux: Sommer, Andreia Gianotti, Rozelle, Sarah S., Sullivan, Spencer, Mills, Jason A., Park, Seon-Mi, Smith, Brenden W., Iyer, Amulya M., French, Deborah L., Kotton, Darrell N., Gadue, Paul, Murphy, George J., Mostoslavsky, Gustavo
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2012
Sujets:
Stem Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499070/
https://ncbi.nlm.nih.gov/pubmed/23149977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4327
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