Residual Expression of Reprogramming Factors Affects the Transcriptional Program and Epigenetic Signatures of Induced Pluripotent Stem Cells

Delivery of the transcription factors Oct4, Klf4, Sox2 and c-Myc via integrating viral vectors has been widely employed to generate induced pluripotent stem cell (iPSC) lines from both normal and disease-specific somatic tissues, providing an invaluable resource for medical research and drug develop...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sommer, Cesar A., Christodoulou, Constantina, Gianotti-Sommer, Andreia, Shen, Steven S., Sailaja, Badi Sri, Hezroni, Hadas, Spira, Avrum, Meshorer, Eran, Kotton, Darrell N., Mostoslavsky, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522693/
https://ncbi.nlm.nih.gov/pubmed/23272148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051711
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados